NITRIC OXIDE IN AGNIHOTRA, YOGA, AYURVEDA AND THE VEDAS- CAPT AJIT VADAKAYIL
One of my readers by the name of Chanchal accused me of penning all "light weight" topics in the recent past.
Well I have to cater to all types of readers.
Some love to read light topics-- Dhimaag pe tension nahi maangta !
Let me choose a HEAVY subject -- Nitric Oxide .
Recently India's best selling author(sic), Chetan Bhagat was set up by a Indian foreign funded TV channel to finger -- nay ambush , Yoga guru, Ramdev in a Conclave full of important celebrities -- by asking him if he can cure homosexuality.
Ramdev had said somewhere that he can cure addictions and vices by Yoga.
So in prime time Walmart lover and "all that is phoren" lover , Chetan Bhagat , found it necessary to insult a respected guest speaker --
-- and that would have made Hindu basher WTE ( waitress turned empress ) and her cotiere of pseudo Hindus who love the Queen Bee more than their mother land , very happy-- not to speak of Vatican.
So I dedicate this post to all those PUSSIES who look at themselves in the mirror and see a lion.
So, my dear PUSSIES -- here we go!
In Hinduism our king mantra is OM. The Christians lifted it and made it AMEN, which does NOT work.
In all my previous posts I have explained that chanting OM boosts the production of Nitric Oxide in the body. I did NOT expound the Chemical gas Nitric Oxide-- I shall do so now.
Mind you, recently 3 scientists were given the Nobel prize for Nitric Oxide, which is lifted from Vedas. The father of Indian medicine Susruta knew about Nitric Oxide as early as 4200 BC.
Punch into Google search FATHER OF MEDICINE , SUSHRUTA- VADAKAYIL.
I had written about Agnihotra , which is a ancient Hindu Homan --which involves cow shit, ghee , rice and a copper urn.
And a lot of the psuedo intelligenstia sort of went -- YECH!
This post is for these PUSSIES too.
Punch into Google search AGNIHOTRA VADAKAYIL.
For production of Nitric Oxide in the body I has written a post ( for DNA strand repair and mutation after 21st Dec 2012 ) . Punch into Google search SO HAM MANTRA VADAKAYIL.
I had written about human hibernation ( who nobody has cracked till now --and who ever cracks it will get the Nobel Prize ) ,how Nitric Oxide works in tandem with Hydrogen Sulphide.
Punch into Google search HIBERNATION VADAKAYIL.
Getting to the point--
What is this Nitric Oxide? What makes it the cat's whiskers of future medicine and research ?
Nitric oxide is a molecule that our body produces to help its 50 trillion cells communicate with each other by transmitting signals throughout the entire body.
People with diabetes usually have lower levels of Nitric oxide than patients without diabetes.
Treating cut flowers and other plants with Nitric oxide has been shown to lengthen the time before wilting.
The Opiate drug Morphine , the addictive pain killer, works by an increase in Nitric Oxide release.
Nitroglycerin and Amyl Nitrite tablets serve as vasodilators because they are converted to Nitric Oxide in the body, to ease angina pain ( heart pain ).
Viagra which gives old lecherous rich men a hard on , works due to its action on Nitric oxide.
In London 2012 Olympics, you saw weight lifters smelling something very strong, seconds before a final lift. Well this is Nitric Oxide gas-- and this is real chemical cheating. They cant be caught as the effect wears away before the lab test.
Actors like Hritik Roshan, Sharukh Khan , Amir Khan etc suddenly pop up within a month with great muscles and sixpacks, due to Nitric oxide steroid supplements specially made for athletes and bodybuilders. These chemicals are bad for health. But Nitric Oxide produced by the body chemical factory is natural, healthy and without side effects.
AAAHA! I can see that all of you men, women, the gender challenged-- all are wide awake now -- and are droolin' for a piece of the Nitric Oxide pie!
Right, time to get scientific! So here we go--
Nitrogen constitutes 78 percent of Earth's atmosphere and is a constituent of all living tissues. Nitrogen is an essential element for life, because it is a constituent of DNA and, as such, is part of the genetic code.
Nitric oxide is a gas that affects blood vessels. It is a simple molecule, having two atoms - nitrogen and oxygen. But it does an incredible array of things. Our blood vessels make nitric oxide. It's a potent and facile dilator.
Nitric oxide or nitrogen monoxide, molecule has the chemical formula NO. It is a free radical and is an important intermediate in the chemical industry.
When the human body reaches the age of 27 years, the secretion of nitric oxide is at its peak. As you get older and the production of nitric oxide in the human body declines gradually, more from age 42 onwards.
Nitric oxide is a by-product of combustion of substances in the air, as in automobile engines, fossil fuel power plants, and is produced naturally during the electrical discharges of lightning in thunderstorms.
In mammals including humans, NO is an important cellular signaling molecule involved in many physiological and pathological processes. It is a powerful vasodilator with a short half-life of a few seconds in the blood.
Nitric oxide controls blood flow in our body. It controls our vascular resistance , the blood pressure . When your body produces sufficient amounts of Nitric oxide, then your blood vessels are relaxed, and your blood pressure is low.
Conversely if you're not making enough or Nitric Oxide production is inactivated, then your blood vessels become contracted and your blood pressure shoots up. So this is an important feature of the blood vessels is its ability to control its own diameter automatically.
The endothelium (inner lining) of blood vessels uses Nitric oxide to signal the surrounding smooth muscle to relax, thus resulting in vasodilation and increasing blood flow. Nitric oxide is highly reactive (having a lifetime of a few seconds), yet diffuses freely across membranes.
Nitric oxide is part of the body's self-defense mechanism.It can defend against bacteria. It also defends against tumor cells. Nitric Oxide in higher concentrations can actually halt the growth of cells or can halt bacterial growth, so it's a defense against infection. Macrophages, certain cells of the immune system, produce Nitric oxide in order to kill invading bacteria.
It is a defense against tumor and cancer. It is a defense against hardening of the arteries too.
Normally, in a young person who does not have hardened arteries, the blood vessels make sufficient amounts of Nitric oxide, and there is no need to take any medicine. When people get old and have heart problems due to hardened arteries and angina pain, you can give Nitric oxide - (nitroglycerin in a pill kept under the tongue ).
Or you can improve the release of Nitric oxide from the blood vessels themselves and enhance the body's ability to make Nitric oxide, or for the matter, protect Nitric oxide from being broken down.
Nitric oxide - is our self-defense system against athrosclerosis. The endothelial lining of the blood vessel is like Teflon. It keeps things from sticking to the vessel wall. The reason it has this property of Teflon is because it releases nitric oxide, so it's a non-sticky surface because it's releasing nitric oxide, which not only relaxes the blood vessel but also prevents things from sticking to the vessel.
Nitric Oxide is of critical importance as a mediator of vasodilation in blood vessels. The vasodilatory actions of Nitric oxide plays a key role in renal control of extracellular fluid homeostasis and is essential for the regulation of blood flow and blood pressure.
Nitroglycerin, Amyl nitrite, "poppers" (isobutyl nitrite or similar) and other nitrite derivatives are used in the treatment of heart disease and Angine pectoris. The compounds get converted to Nitric oxide which in turn dilates the coronary artery (blood vessels around the heart), thereby increasing its blood supply. These drugs, however, are predominantly venodilators, dilating peripheral veins and hence reducing venous return and preload to the heart.
This reduces the oxygen requirement of the myocardium and subsequently lessens the heart pain. By dilating (expanding) the veins, Nitric oxide drugs lower arterial pressure and left ventricular filling pressure.This vasodilation does not decrease the volume of blood the heart pumps, but rather it decreases the force the heart muscle must exert to pump the same volume of blood.
The interior surface (endothelium) of your arteries produce nitric oxide. When plaque builds up in your arteries, called atherosclerosis, you reduce your capacity to produce Nitric oxide, which is why physicians prescribe nitroglycerin for heart and stroke patients.
As I said before Nitric Oxide plays a role in erection of the penis. The vasodilatatory effect of Nitric Oxide plays a vital role in the development and maintenance of a penile erection. Vasodilation of blood vessels results in more blood flowing in and hence erection. This is the biological basis of Sildenafil (Viagra), which works to inhibit the enzyme phosphodiesterase PDE5.
Basically Viagra, stimulates erections primarily by enhancing signaling through the nitric oxide pathway in the penis. Old guys with with atherosclerosis, diabetes, or hypertension often show impaired Nitric Oxide pathways— and hence, sorry, NO hop!
Nitric oxide also serves as a neurotransmitter between nerve cells, part of its general role in redox signaling. Unlike most other neurotransmitters that only transmit information from a presynaptic to a postsynaptic neuron, the small, uncharged, and fat-soluble nitric oxide molecule can diffuse widely and readily enters cells.
Nitric oxide is an important neurotransmitter in various parts of the gastrointestinal tract. It causes relaxation of the gastrointestinal smooth muscle. In the stomach it increases the capacity of the fundus to store food and fluids.
Nitric oxide acts on cardiac muscle to decrease contractility and heart rate. Nitric oxide contributes to the regulation of cardiac contractility. Evidence suggests that coronary artery disease (CAD) is related to defects in generation or action of Nitric Oxide.
Reduced levels of exhaled Nitric Oxide have been associated with exposure to traffic related air pollution. Nitric Oxide is required for division and proliferation after DNA damage has been repaired. A gene was described that increases nitric oxide production after UV radiation.
Diminished supply of nitric oxide can lead to vascular damage, such as endothelial dysfunction and vascular inflammation. Vascular damage can lead to decreased blood flow to the extremities, causing the diabetic patient to be more likely to develop Neuropathy, non-healing ulcers, and be at a greater risk for lower limb amputation.
Diabetes patients have less Nitric Oxide. They don’t have good sensation; they tend not to know where their feet are in space and they trip over the curb. Nitric oxide regulates wound healing and tendon healing.
Dietary nitrate is an important source of Nitric oxide in mammals. Green, leafy vegetables, lettuce, and some root vegetables (such as beetroot) have high concentrations of nitrate. When eaten and absorbed into the bloodstream nitrate is concentrated in saliva (about 10 fold) and is reduced to nitrite on the surface of the tongue by a biofilm of commensal facultative anaerobic bacteria.
This nitrite is swallowed and reacts with acid and reducing substances in the stomach (such as ascorbate) to produce high concentrations of nitric oxide. The purpose of this mechanism to create Nitric oxideis for sterilization of swallowed food, to prevent food poisoning and to maintain gastric mucosal blood flow.
A similar mechanism is protects the skin from fungal infections, where nitrate in sweat is reduced to nitrite by skin commensal organisms and then to Nitric Oxide on the slightly acidic skin surface.
A major natural source of Nitric Oxide is lightning. The use of internal combustion engines has drastically increased the presence of nitric oxide in the environment. One purpose of catalytic converters in cars is to minimize Nitric Oxide emission by catalytic reversion to O2 and N2.
Nitric oxide is rapidly oxidised in air to nitrogen dioxide. When exposed to oxygen, Nitric oxide is converted into nitrogen dioxide.
2 NO + O2 → 2 NO2
In water, Nitric oxide reacts with oxygen and water to form HNO2 or nitrous acid.
4 NO + O2 + 2 H2O → 4 HNO2
In the laboratory, Nitric oxide is conveniently generated by reduction of dilute nitric acid with copper:
8 HNO3 + 3 Cu → 3 Cu(NO3)2 + 4 H2O + 2 NO
Nitric oxide in the air may convert to Nitric acid, which has been implicated in acid rain. However, it is an important source of nutrition for plant life in the form of nitrates. Furthermore, both NO and NO2 participate in ozone layer depletion.
Nitric oxide is a small highly diffusible gas and a ubiquitous bioactive molecule. It is a known bioproduct in almost all type of organisms, ranging from bacteria to plants, fungi and animal cells.
Nitric oxide concentration can be determined using a simple chemiluminescent reaction involving ozone. A sample containing nitric oxide is mixed with a large quantity of ozone. The nitric oxide reacts with the ozone to produce oxygen and nitrogen dioxide.
This reaction also produces light (chemiluminescence), which can be measured with a photodetector. The amount of light produced is proportional to the amount of nitric oxide in the sample.
NO + O3 → NO2 + O2 + light
Nitric oxide therapy has the potential to significantly increase the quality of life and, in some cases, save the lives of infants at risk for pulmonary vascular disease. Currently in the United States nitric oxide is a gas available in 100 ppm and 800 ppm concentrations.
Nitric oxide is a compound produced by many cells of the body. When inhaled, nitric oxide dilates the pulmonary vasculature, and because of efficient scavenging by hemoglobin, has minimal effect on the vasculature of the entire body.
Nitric oxide is absorbed systemically after inhalation. Most of it move across the pulmonary capillary bed where it combines with hemoglobin that is 60% to 100% oxygen-saturated.
Nitrate has been identified as the predominant nitric oxide metabolite excreted in the urine, accounting for >70% of the nitric oxide dose inhaled. Nitrate is cleared from the plasma by the kidney .
Nitric Oxide improves blood and plasma circulation and thus increases nutrient flow to the cells.. It decreases oedema and swelling as lymph drainage happens better. If somebody has an infection, you can get the anti-biotic more easily to the site of the infection and kill the bacteria or virus. Nitric Oxide restores blood flow to nerves, nerves which may be responsible for pain.
Yoga will increase the natural nitric oxide levels in the body as by exercising an enzyme production increases in the body which has a tendency of producing nitric oxide.
Muscle gain can be achieved by nitric oxide and this is why body builders are involved in the nitric oxide supplement consumption more.
Nitric oxide makes the immune system of our body stronger and gives a fast recovery to the body in case of any ruptures. Nitric Oxide is absolutely crucial to your well-being and is regarded as the most significant molecule in the body. It stimulates your brain , and you wont be a DUD with Alzheimers .
Nitric Oxide is almost as important to humans as oxygen. More blood flow means better oxygen transfer and more energy. Nitric Oxide also has important properties in the immune system where it helps us fight off infections. It is important in the nervous system where it helps our brain cells communicate properly.
It can reverse cardiovascular impairment naturally and age-proof your cardiovascular system. It's the body's way of preventing strokes and heart attacks. Nitric oxide helps blood vessels relax and allows more blood to reach heart and organs.
Nitric oxide is naturally produced in the body and is known as a “messenger molecule,” because it helps the cells of the body communicate with one another. Nitric oxide levels tend to decline as we age. This is especially true for those who eat junk Western GM foods.
Increasing nitric oxide has become the new secret weapon for athletes and bodybuilders. Athletes are now taking supplements with L-arginine and L-citrulline to increase the flow of blood and oxygen to the skeletal muscle which can augment strength and endurance.
They also use them to facilitate the removal of exercise-induced lactic acid build-up which reduces fatigue and recovery time. Since arginine levels become depleted during exercise, the entire arginine-nitric oxide - citrulline loop can lose efficiency, causing less-than-ideal Nitric oxide levels and higher lactate levels. Supplements can help restore this loop allowing for better workouts and faster recovery from workouts.
People with Piriformis Syndrome ( sciatic nerve ) pay attention--as Nitric oxide is anti-inflammatory . IR light can also increase Nitric Oxide and reduce spot pain. Eat Nitric Oxide rich foods like lettuce , spinach ( like Popeye ) and beetroot. It improves sleep at night, and so you wont feel the dull pain.
Grace and peace!
Modern science has NOT yet found out the partnership between Nitric Oxide and Hydrogen Sulphide, which was known to Indian 7000 years ago.
Like H2S , Nitric Oxide is a bio signaler. Hydrogen sulfide (H2S), from cow dung has its own certain functions similar to those of nitric oxide (NO), is actually a partner with NO in growing new blood vessels .
People with diabetes usually have lower levels of Nitric oxide than patients without diabetes. Both H2S and NO relaxes blood vessels-- and the miracle part is that they share the job, in a QUID PRO QUO manner, and a Tamas-Rajas (Yin-Yang..) manner.
CAPT AJIT VADAKAYIL
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